[Namron] alcohol question
Lee McGoodwin
etienett at yahoo.com
Sun Dec 28 23:25:33 PST 2003
Susan,
Found this on-lline. Does it help?
Etienett
Moderate alcohol intake has been associated with a
decreased risk of cardiovascular disease,1,2 which may
be mediated by high-density lipoprotein cholesterol
(HDL-C).3 Evidence indicates that alcohol intake
increases HDL-C concentrations. For example, Thornton
and colleagues showed that consumption of half a
bottle of white wine (39 g alcohol) per day for 6
weeks significantly (P < 0.01) increased mean HDL-C
levelsfrom 41 to 48 mg/dLin 12 healthy,
normolipidemic subjects (nine women and three men).4
None of the subjects was taking medication, and none
smoked tobacco. The subjects' wine intake did not
significantly change total plasma cholesterol
(Total-C), total triglyceride (Total-TG), or
low-density lipoprotein cholesterol (LDL-C)
concentrations. However, one must consider the
calories added to the diet by alcohol use. For
example, the 39 g of alcohol consumed per day for 42
days in this study represent a total of 11,466
additional caloriesthe equivalent of 3 lbs of
additional weight (11,466 cal ÷ 3,600 cal/lb) over 6
weeks, or approximately 27 lbs per year! A more
moderate alcohol intake was described by McConnell et
al.5 In this study, 20 healthy nonsmokers (11 men and
9 women; aged 2351 years) completed a 10-week program
of controlled alcohol consumption, which consisted of
2 weeks of alcohol abstention; 6 weeks of alcohol use
(one 12-ounce beer13.5 g of ethyl alcoholeach
evening); and 2 additional weeks of abstention.
Compared with the mean abstention level, the mean
HDL-C level significantly (P = 0.03) increased 2 mg/dL
(from 52 to 54 mg/dL) after consumption of a single,
daily alcoholic beverage for 6 weeks. LDL-C,
very-low-density-lipoprotein cholesterol (VLDL-C), TG,
and apolipoprotein levels were not significantly
changed.
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