Vicodin- wasRe: [Sca-cooks] Offline

Sue Clemenger mooncat at in-tch.com
Tue May 14 06:41:34 PDT 2002


It sure seems to on me! I ended up with quite an assortment of both
after my knee surgeries, and a half-dose of either makes me very, very
loopy.  I called the dr., and asked if I could *please* just use
Alleve.  Saved the stronger stuff for migraine-whompers.
--Maire, wondering if some of us are *extra* sensitive? and what causes
that?

Avraham haRofeh wrote:
>
> > Funny- that's one of the ones that does absolutely
> > nothing for me, neither kill the pain, nor give me a
> > buzz. My surgeon put me on a hefty dose after some
> > surgery, and I had to call him back and ask for some
> > Tylenol 3....
>
> Some people lack the enzyme that metabolizes hydrocodone to morphine. Some
> people also lack the enzyme that metabolizes codeine to morphine (about 10%
> of the population in the US). That's why some of these drugs don't work for
> everyone.
>
> Note that Lortab = Vicodin. If one doesn't work, neither will the other. I'm
> not sure about Percocet (oxycodone), whether it uses the same pathway as
> either of these others.
>
> Avraham



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